WANG Bao-qiang,YANG Xiao-ping,LI Yong-hong.Optimization of Tech-Parameters for Medicine Extraction in Crocus Sativus L. based on HIU[J].Journal of Chengdu University of Information Technology,2016,(04):372-376.
藏红花药物高能超声提取的工艺参数优化
- Title:
- Optimization of Tech-Parameters for Medicine Extraction in Crocus Sativus L. based on HIU
- 文章编号:
- 2096-1618(2016)04-0372-05
- Keywords:
- biological engineering; Chinese tibetan medicine; extraction of Crocus Sativus L.; high intensity ultrasound(HIU); acoustical cavitation; ultrasonic chemistry-method; parameter optimization
- 分类号:
- TB556
- 文献标志码:
- A
- 摘要:
- 高能超声空化效应运用于中药成分提取的关键问题是工艺设计的科学性。为揭示超声空化效应的作用机制,探索藏红花超声提取工艺的最佳化,采取理论分析和实验验证,对高能超声提取中药的作用机制进行了研究,并基于藏红花提取物药用成分的HPLC检测数据,实现超声提取工艺的参数优化。研究结果表明,超声空化效应的能量特征及其作用机制是可控的。另外,依据提取物中主要成分(Crocus-I和Crocus-II)含量最大化原则,得知藏红花超声提取工艺的最佳参数为:功率密度为2.0～3.0 W/cm3; 提取时间为20～30 min。
- Abstract:
- The key problem for Chinese medicine based on HI ultrasonic cavitation is the technique scientificalnes. For understanding the reaction mechanism of ultrasonic cavitation and the technical optimization of extracting Crocus sativus L based on the content of medicine composition in extraction. The mechanism of ultrasonic extraction through the theory and experiment are used for obtaining the technique optimization according to the data of HPLC detection. The conclusions are that the characters of ultrasonic energy could be controlled and the best technical characters are. The power density is 2.0-3.0 W/cm3 and the extracting time is 20-30 min according to the content maximization.
参考文献/References:
[1] Doche ML, Hihn JY.Influence of ultrasound power and frequency upon corrosion kinetics of zincin saline media[J]. Ultrasonics sonochemistry,2008,10(6):357-362.
[2] 黄璐琦,王永炎.中药材质量标准研究[M].北京:人民卫生出版社,2010.
[3] Hromadkova Z. Ultrasonic extraction of plant materials-investigation of hemicellulose release from buckwheat hulls[J].Ultrasonics sonochemistry, 2003,10(3):127-133.
[4] 王保强,尹蓉莉.超声生物材料处理与声学参数的调控[J].生物医学工程学杂志,2004,20(5):662-665.
[5] Wang Bao-qiang, Deng Changjian,Li Yiding. The design optimization of ultrasonic equipment for Chinese traditional medicine extraction[J]. IEEE Proc. of 06'ICMA, 2006:463-468.
[6] Feng R,Zhao YY,Zhu CP. Mason TJ. Enhancement of ultrasonic cavitation yield by multi-frequency sonication[J]. Ultrasonics sonochemistry,2002,9(5):231-236.
[7] Manef Chtourou, Rami Abdelhédi. Solvent free synthesis of 2-propenones catalyzed by commercial acid-clays under ultrasound irradiation[J].Ultrasonics Sonochemistry,2010,17:246-249.
[8] 季文军,代文婷.中药藏红花的研究概况[J].Strait Pharmaceutical Journal(海峡药学),2011,23(10).
[9] Moussatov A.Cone-like bubble formation in ultrasonic cavitation field[J].Ultrasonics sonochemistry,2009,10(4):191-195.
[10] S.Gereshetc. Characterization of the extracellular polysaccharde of porphyridium sp.:molecular weight determination and rheological properties[J].Carbohydrate Polymers, 2009,50(2):183-189.
[11] Gogate PR, Wilhelm AM.Some aspects of the design of sonochemical reactors[J]. Ultrasonics sono- chemistry,2007,10(6):325-330.
[12] Sergio PC, RobertaS. Effects of sonication on the Reactivity of Chitin Toward its Heterogeneous deacetylation[J].International Journal of Polymeric Materials,2011,5(8):695-700.
[13] Hongmei Lin, Yonggang Zhang, Mei Han,et al.Aqueous ionic liquid based ultrasonic assisted extraction of eight ginsenosides from ginseng root[J].Ultrasonics Sonochemistry,2013,20:680-684.
[14] Yinshi Sun, Zhengbo Liu, Jianhua Wang,et al.Aqueous ionic liquid based ultrasonic assisted extraction of four acetophenones from the Chinese medicinal plant Cynanchum bungei Decne[J].Ultrasonics Sonochemistry, 2013,20:180-186.
备注/Memo
收稿日期:2016-08-01 基金项目:四川省科技计划资助项目(2014SZ0216)